As the successor of Giorgio Vasari (1511 – 1574) to head the Accademia del Disegno, Ligozzi also became an important source for the influence of Venetian art in Florence. With this Venetian influence of Color, it enhanced Ligozzi’s Mannerist painting style and sculpture-like figures, as influence by Michelangelo. Born in Verona to a family of artists and craftsmen, Ligozzi became a successful painter, illustrator, designer and miniaturist, active mostly in Florence. His father, Giovanni Ermanno Ligozzi (1572 – 1605), was also a painter, as was his brother Francesco and his cousin Francesco di Mercurio.
Before settling in Florence in 1576, he was an artist for the Hapsburg Court of the Austrian Empire in the city of Vienna. From this illustrious position, he found another in Florence with several patrons from the Medici family. Additional to his religious and mythological depictions, he also painted and drew several works of fauna and flora. These works were not just artistic decorations, but highly detailed depictions used for the scientific records of Medici patrons and the Italian naturalist, Ulisse Aldrovandi (1522 – 1605).
An example of his soft Venetian coloring, monumental figures and strong composition can be seen in his Sacrifice of Isaac, now in the Uffizi Gallery. On several of his miniature works he used the signature, “di minio.” Ligozzi had some pupils including his son, Francesco (1585 – 1641) and Donato Mascagni (1579 – 1636).